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The Journal of Neuroscience : the... Oct 2018Motor and premotor cortices are crucial for the control of movements. However, we still know little about how these areas contribute to higher-order motor control, such... (Review)
Review
Motor and premotor cortices are crucial for the control of movements. However, we still know little about how these areas contribute to higher-order motor control, such as deciding which movements to make and when to make them. Here we focus on rodent studies and review recent findings, which suggest that-in addition to motor control-neurons in motor cortices play a role in sensory integration, behavioral strategizing, working memory, and decision-making. We suggest that these seemingly disparate functions may subserve an evolutionarily conserved role in sensorimotor cognition and that further study of rodent motor cortices could make a major contribution to our understanding of the evolution and function of the mammalian frontal cortex.
Topics: Animals; Humans; Motor Cortex; Movement; Prefrontal Cortex; Touch; Vibrissae
PubMed: 30381432
DOI: 10.1523/JNEUROSCI.1671-18.2018 -
Philosophical Transactions of the Royal... Nov 2011Active sensing systems are purposive and information-seeking sensory systems. Active sensing usually entails sensor movement, but more fundamentally, it involves control...
Active sensing systems are purposive and information-seeking sensory systems. Active sensing usually entails sensor movement, but more fundamentally, it involves control of the sensor apparatus, in whatever manner best suits the task, so as to maximize information gain. In animals, active sensing is perhaps most evident in the modality of touch. In this theme issue, we look at active touch across a broad range of species from insects, terrestrial and marine mammals, through to humans. In addition to analysing natural touch, we also consider how engineering is beginning to exploit physical analogues of these biological systems so as to endow robots with rich tactile sensing capabilities. The different contributions show not only the varieties of active touch--antennae, whiskers and fingertips--but also their commonalities. They explore how active touch sensing has evolved in different animal lineages, how it serves to provide rapid and reliable cues for controlling ongoing behaviour, and even how it can disintegrate when our brains begin to fail. They demonstrate that research on active touch offers a means both to understand this essential and primary sensory modality, and to investigate how animals, including man, combine movement with sensing so as to make sense of, and act effectively in, the world.
Topics: Animals; Arthropod Antennae; Fingers; Humans; Movement; Touch; Vibrissae
PubMed: 21969680
DOI: 10.1098/rstb.2011.0167 -
Sensors (Basel, Switzerland) Apr 2022Whisker sensors are a class of tactile sensors that have recently attracted attention. Inspired by mammals' whiskers known as mystacial vibrissae, they have displayed... (Review)
Review
Whisker sensors are a class of tactile sensors that have recently attracted attention. Inspired by mammals' whiskers known as mystacial vibrissae, they have displayed tremendous potential in a variety of applications e.g., robotics, underwater vehicles, minimally invasive surgeries, and leak detection. This paper provides a supplement to the recent tactile sensing techniques' designs of whiskers that only sense at their base, as well as the materials employed, and manufacturing techniques. The article delves into the technical specifications of these sensors, such as the resolution, measurement range, sensitivity, durability, and recovery time, which determine their performance. The sensors' sensitivity varies depending on the measured physical quantity; for example, the pressure sensors had an intermediate sensitivity of 58%/Pa and a response time of around 90 ms, whereas the force sensors that function based on piezoelectric effects exhibited good linearity in the measurements with a resolution of 3 µN and sensitivity of 0.1682 mV/µN. Some sensors were used to perform spatial mapping and the identification of the geometry and roughness of objects with a reported resolution of 25 nm. The durability and recovery time showed a wide range of values, with the maximum durability being 10,000 cycles and the shortest recovery time being 5 ms. Furthermore, the paper examines the fabrication of whiskers at the micro- and nanoscales, as well as their contributions to mechanical and thermal behavior. The commonly used manufacturing techniques of 3D printing, PDMS casting, and screen printing were used in addition to several micro and nanofabrication techniques such as photolithography, etching, and chemical vapor deposition. Lastly, the paper discusses the main potential applications of these sensors and potential research gaps in this field. In particular, the operation of whisker sensors under high temperatures or high pressure requires further investigation, as does the design of sensors to explore larger topologies.
Topics: Animals; Mammals; Printing, Three-Dimensional; Robotics; Touch; Vibrissae
PubMed: 35408319
DOI: 10.3390/s22072705 -
Physiological Reviews Jan 2021The array of whiskers on the snout provides rodents with tactile sensory information relating to the size, shape and texture of objects in their immediate environment.... (Review)
Review
The array of whiskers on the snout provides rodents with tactile sensory information relating to the size, shape and texture of objects in their immediate environment. Rodents can use their whiskers to detect stimuli, distinguish textures, locate objects and navigate. Important aspects of whisker sensation are thought to result from neuronal computations in the whisker somatosensory cortex (wS1). Each whisker is individually represented in the somatotopic map of wS1 by an anatomical unit named a 'barrel' (hence also called barrel cortex). This allows precise investigation of sensory processing in the context of a well-defined map. Here, we first review the signaling pathways from the whiskers to wS1, and then discuss current understanding of the various types of excitatory and inhibitory neurons present within wS1. Different classes of cells can be defined according to anatomical, electrophysiological and molecular features. The synaptic connectivity of neurons within local wS1 microcircuits, as well as their long-range interactions and the impact of neuromodulators, are beginning to be understood. Recent technological progress has allowed cell-type-specific connectivity to be related to cell-type-specific activity during whisker-related behaviors. An important goal for future research is to obtain a causal and mechanistic understanding of how selected aspects of tactile sensory information are processed by specific types of neurons in the synaptically connected neuronal networks of wS1 and signaled to downstream brain areas, thus contributing to sensory-guided decision-making.
Topics: Animals; Brain Diseases; Brain-Computer Interfaces; Humans; Mice; Neural Pathways; Sensation; Signal Transduction; Somatosensory Cortex; Vibrissae
PubMed: 32816652
DOI: 10.1152/physrev.00019.2019 -
PloS One 2023Facial vibrissae (whiskers) are thin, tapered, flexible, hair-like structures that are an important source of tactile sensory information for many species of mammals. In...
Facial vibrissae (whiskers) are thin, tapered, flexible, hair-like structures that are an important source of tactile sensory information for many species of mammals. In contrast to insect antennae, whiskers have no sensors along their lengths. Instead, when a whisker touches an object, the resulting deformation is transmitted to mechanoreceptors in a follicle at the whisker base. Previous work has shown that the mechanical signals transmitted along the whisker will depend strongly on the whisker's geometric parameters, specifically on its taper (how diameter varies with arc length) and on the way in which the whisker curves, often called "intrinsic curvature." Although previous studies have largely agreed on how to define taper, multiple methods have been used to quantify intrinsic curvature. The present work compares and contrasts different mathematical approaches towards quantifying this important parameter. We begin by reviewing and clarifying the definition of "intrinsic curvature," and then show results of fitting whisker shapes with several different functions, including polynomial, fractional exponent, elliptical, and Cesàro. Comparisons are performed across ten species of whiskered animals, ranging from rodents to pinnipeds. We conclude with a discussion of the advantages and disadvantages of using the various models for different modeling situations. The fractional exponent model offers an approach towards developing a species-specific parameter to characterize whisker shapes within a species. Constructing models of how the whisker curves is important for the creation of mechanical models of tactile sensory acquisition behaviors, for studies of comparative evolution, morphology, and anatomy, and for designing artificial systems that can begin to emulate the whisker-based tactile sensing of animals.
Topics: Animals; Vibrissae; Mammals; Touch; Touch Perception; Caniformia
PubMed: 36607960
DOI: 10.1371/journal.pone.0269210 -
Anatomical Record (Hoboken, N.J. : 2007) Mar 2022Most cetaceans are born with vibrissae but they can be lost or reduced in adulthood, especially in odontocetes. Despite this, some species of odontocetes have been found...
Most cetaceans are born with vibrissae but they can be lost or reduced in adulthood, especially in odontocetes. Despite this, some species of odontocetes have been found to have functioning vibrissal follicles (including the follicle itself and any remaining vibrissal hair shaft) that play a role in mechanoreception, proprioception and electroreception. This reveals a greater diversity of vibrissal function in odontocetes than in any other mammalian group. However, we know very little about vibrissal follicle form and function across the Cetacea. Here, we qualitatively describe the gross vibrissal follicle anatomy of fetuses of three species of cetaceans, including two odontocetes: Atlantic white-sided dolphin (Lagenorhynchus acutus), harbour porpoise (Phocoena phocoena), and one mysticete: minke whale (Balaenoptera acutorostrata), and compared our findings to previous anatomical descriptions. All three species had few, short vibrissae contained within a relatively simple, single-part follicle, lacking in muscles. However, we observed differences in vibrissal number, follicle size and shape, and innervation distribution between the species. While all three species had nerve fibers around the follicles, the vibrissal follicles of Balaenoptera acutorostrata were innervated by a deep vibrissal nerve, and the nerve fibers of the odontocetes studied were looser and more branched. For example, in Lagenorhynchus acutus, branches of nerve fibers travelled parallel to the follicle, and innervated more superficial areas, rather than just the base. Our anatomical descriptions lend support to the observation that vibrissal morphology is diverse in cetaceans, and is worth further investigation to fully explore links between form and function.
Topics: Animals; Cetacea; Dolphins; Hair Follicle; Vibrissae
PubMed: 34288543
DOI: 10.1002/ar.24714 -
Neuroscience Jan 2018Rodents use an array of long tactile facial hairs, the vibrissae, to locate and discriminate objects. Each vibrissa is densely innervated by multiple different types of... (Review)
Review
Rodents use an array of long tactile facial hairs, the vibrissae, to locate and discriminate objects. Each vibrissa is densely innervated by multiple different types of trigeminal (TG) sensory neurons. Based on the sensory ending morphology, there are at least six types of vibrissa innervating neurons; whereas based on electrophysiological recordings, vibrissa neurons are generally classified as rapidly adapting (RA) and slowly adapting (SA), and show different responses to whisking movement and/or touch. There is a clear missing link between the morphologically defined neuronal types and their exact physiological properties and functions. We briefly summarize recent advances and consider single-cell transcriptome profiling, together with optogenetics-assisted in vivo electrophysiology, as a way to fill this major gap in our knowledge of the vibrissa sensory system.
Topics: Adaptation, Physiological; Animals; Electrophysiological Phenomena; Gene Expression Profiling; Optogenetics; Sensory Receptor Cells; Touch Perception; Vibrissae
PubMed: 28673712
DOI: 10.1016/j.neuroscience.2017.06.033 -
Annals of the New York Academy of... Apr 2011The somatosensory cortex of many rodents, lagomorphs, and marsupials contains distinct cytoarchitectonic features named "barrels" that reflect the pattern of large... (Review)
Review
The somatosensory cortex of many rodents, lagomorphs, and marsupials contains distinct cytoarchitectonic features named "barrels" that reflect the pattern of large facial whiskers on the snout. Barrels are composed of clustered thalamocortical afferents relaying sensory information from one whisker surrounded by cell-dense walls or "barrels" in layer 4 of the cortex. In many ways, barrels are a simple and relatively accessible canonical cortical column, making them a common model system for the examination of cortical development and function. Despite their experimental accessibility and popularity, we still lack a basic understanding of how and why barrels form in the first place. In this review, we will examine what is known about mechanisms of barrel development, focusing specifically on the recent literature using the molecular-genetic power of mice as a model system for examining brain development.
Topics: Animals; Body Patterning; Hair Follicle; Mice; Models, Biological; Organ Specificity; Somatosensory Cortex; Vibrissae
PubMed: 21534999
DOI: 10.1111/j.1749-6632.2011.06024.x -
Neuroscience Jan 2018Our sensory receptors are faced with an onslaught of different environmental inputs. Each sensory event or encounter with an object involves a distinct combination of... (Review)
Review
Our sensory receptors are faced with an onslaught of different environmental inputs. Each sensory event or encounter with an object involves a distinct combination of physical energy sources impinging upon receptors. In the rodent whisker system, each primary afferent neuron located in the trigeminal ganglion innervates and responds to a single whisker and encodes a distinct set of physical stimulus properties - features - corresponding to changes in whisker angle and shape and the consequent forces acting on the whisker follicle. Here we review the nature of the features encoded by successive stages of processing along the whisker pathway. At each stage different neurons respond to distinct features, such that the population as a whole represents diverse properties. Different neuronal types also have distinct feature selectivity. Thus, neurons at the same stage of processing and responding to the same whisker nevertheless play different roles in representing objects contacted by the whisker. This diversity, combined with the precise timing and high reliability of responses, enables populations at each stage to represent a wide range of stimuli. Cortical neurons respond to more complex stimulus properties - such as correlated motion across whiskers - than those at early subcortical stages. Temporal integration along the pathway is comparatively weak: neurons up to barrel cortex (BC) are sensitive mainly to fast (tens of milliseconds) fluctuations in whisker motion. The topographic organization of whisker sensitivity is paralleled by systematic organization of neuronal selectivity to certain other physical features, but selectivity to touch and to dynamic stimulus properties is distributed in "salt-and-pepper" fashion.
Topics: Afferent Pathways; Animals; Neurons; Rodentia; Somatosensory Cortex; Touch Perception; Vibrissae
PubMed: 28918260
DOI: 10.1016/j.neuroscience.2017.09.014 -
Communications Biology Jun 2023Behavior and innervation suggest a high tactile sensitivity of elephant trunks. To clarify the tactile trunk periphery we studied whiskers with the following findings....
Behavior and innervation suggest a high tactile sensitivity of elephant trunks. To clarify the tactile trunk periphery we studied whiskers with the following findings. Whisker density is high at the trunk tip and African savanna elephants have more trunk tip whiskers than Asian elephants. Adult elephants show striking lateralized whisker abrasion caused by lateralized trunk behavior. Elephant whiskers are thick and show little tapering. Whisker follicles are large, lack a ring sinus and their organization varies across the trunk. Follicles are innervated by ~90 axons from multiple nerves. Because elephants don't whisk, trunk movements determine whisker contacts. Whisker-arrays on the ventral trunk-ridge contact objects balanced on the ventral trunk. Trunk whiskers differ from the mobile, thin and tapered facial whiskers that sample peri-rostrum space symmetrically in many mammals. We suggest their distinctive features-being thick, non-tapered, lateralized and arranged in specific high-density arrays-evolved along with the manipulative capacities of the trunk.
Topics: Animals; Vibrissae; Elephants; Touch; Mammals; Movement
PubMed: 37291455
DOI: 10.1038/s42003-023-04945-5