Gene or Genome
TRG gene
Subclass of:
Genes, T-Cell Receptor
Definitions related to trg gene:
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(t-cell receptor gamma locus) This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. (from LocusLink)NCI ThesaurusU.S. National Cancer Institute, 2021
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(genes, t-cell receptor gamma) DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organized similarly to the TcR beta-chain locus.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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