Pharmacologic Substance
acetaminophen Audio
a·ce·ta·min·o·phen [ uh-see-tuh-min-uh-fuhn, as-i-tuh- ]
Brand Names:
Acephen; Acetadryl; Actamin; Allzital; Anabar; Anacin Advanced Headache Formula; Anacin AF; Apadaz; Arthriten Inflammatory Pain; Arthriten Max; Backaid; Backaid IPF; Backprin; Bactimicina; BF-Paradac; Bupap; By Ache; Capacet; Cetafen; Comtrex Sore Throat Relief; Contragesic; CounterAct Pain; Dologesic; Dvorah; Ed Flex; Endocet; Esgic; Exaprin; Excedrin; Excedrin Back & Body; Excedrin Mild Headache; Excedrin PM; Excedrin PM Triple Action; Excedrin Quick Tab; Excedrin Tension Headache; Femadrine; Feverall; Fioricet; Fioricet with Codeine; Frenadol; Hycet; Legatrin PM; Little Fevers; Lorcet; Lortab; Mapap; Mapap PM; Marten-Tab; Nalocet; Nanomol suspension; Ninjacof A; Norco; Nortemp; Ofirmev; Painaid; Painaid ESF; Pamprin Cramp Formula; Pamprin Max Formula; Pamprin Multi-Symptom; Panadol; Panadol Extra; Panadol PM; Percocet; Percogesic; Percogesic Reformulated Jan 2011; Pharbetol; Phrenilin; Phrenilin Forte; Premsyn PMS; Primlev; Prolate; Relagesic; Repan; Ringl; Saleto; Sedalmex; Sed-Max; Tactinal; Tempra Quicklets; Tencon; Trezix; Tycolene; Tylenol; Tylenol PM; Tylenol with Codeine; Ultracet; Un-Aspirin; Unisom with Pain Relief; Vanatol; Vanquish; Verdrocet; Vicodin; Vitapap; Vtol; Zamicet; Zebutal
Effect:
Central Nervous System Activity Alteration; Decreased Prostaglandin Production; Hypothalamic Endocrine Activity Alteration; Peripheral Nervous System Activity Alteration
May Prevent:
Fever; Pain
May Treat:
Fever; Pain
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to acetaminophen:
  • A common, over-the-counter drug used to reduce fever and relieve mild to moderate pain, but which does not reduce redness or swelling (inflammation).
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A drug that reduces pain and fever (but not inflammation). It belongs to the family of drugs called analgesics.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A p-aminophenol derivative with analgesic and antipyretic activities. Although the exact mechanism through which acetaminophen exert its effects has yet to be fully determined, acetaminophen may inhibit the nitric oxide (NO) pathway mediated by a variety of neurotransmitter receptors including N-methyl-D-aspartate (NMDA) and substance P, resulting in elevation of the pain threshold. The antipyretic activity may result from inhibition of prostaglandin synthesis and release in the central nervous system (CNS) and prostaglandin-mediated effects on the heat-regulating center in the anterior hypothalamus.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Acetaminophen, drug used in the treatment of mild pain, such as headache and pain in joints and muscles, and to reduce fever. Acetaminophen is the major metabolite of acetanilid and phenacetin, which were once commonly used drugs, and is responsible for their analgesic (pain-relieving) effects....
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
  • Tylenol, trademarked brand of acetaminophen, an aspirin-free pain reliever and fever reducer introduced in 1955 by McNeil Laboratories, Inc. (now part of the Johnson & Johnson pharmaceutical conglomerate).
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.