Organic Chemical
phenacetin
phe·nac·e·tin [ fuh-nas-i-tin ]
Effect:
Decreased Prostaglandin Production
May Treat:
Fever;
Pain
More Information:
Definitions related to phenacetin:
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A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic, white crystalline solid that is slightly soluble in water and benzene, soluble in acetone and very soluble in pyrimidine. It is used in research as the preferred marker for detecting CYP1A2-based inhibition potential in vitro. Human ingestion of phenacetin can result in a bluish discoloration of the skin due to a lack of oxygen in the blood (cyanosis), dizziness and respiratory depression. It is reasonably anticipated to be a human carcinogen. (NCI05)NCI ThesaurusU.S. National Cancer Institute, 2021
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