Antibiotic
amikacin
[ am-i-key-sin ]
Brand Names:
Arikayce
Effect:
Decreased Protein Synthesis
May Treat:
Acinetobacter Infections;
Bone Diseases, Infectious;
Burns;
Central Nervous System Infections;
Endocarditis;
Escherichia coli Infections;
Intraabdominal Infections;
Klebsiella Infections;
Mycobacterium Infections;
Proteus Infections;
Pseudomonas Infections;
Respiratory Tract Infections;
Sepsis;
Serratia Infections;
Skin Diseases, Infectious;
Soft Tissue Infections;
Staphylococcal Infections;
Surgical Wound Infection;
Urinary Tract Infections
More Information:
Definitions related to amikacin:
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A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.NCIU.S. National Cancer Institute, 2021
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An antibiotic drug used to treat infection. It belongs to the family of drugs called aminoglycoside antibiotics.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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