Pharmacologic Substance
amlodipine
Brand Names:
Azor; Caduet; Consensi; Exforge; Exforge HCT; Katerzia; Lotrel; Norvasc; Prestalia; Tribenzor; Twynsta
Effect:
Coronary Arterial Vasodilation; Decreased Blood Pressure
May Treat:
Angina Pectoris, Variant; Coronary Artery Disease; Hypertension
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to amlodipine:
  • A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug resistance (MDR) activity through inhibition of the p-glycoprotein efflux pump.
    NCI
    U.S. National Cancer Institute, 2021
  • Long-acting dihydropyridine calcium channel blocker; it is effective in the treatment of angina pectoris and hypertension.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.