Pharmacologic Substance
nifedipine
ni·fed·i·pine
Brand Names:
Adalat; Afeditab CR; Procardia
Effect:
Coronary Arterial Vasodilation; Decreased Blood Pressure
May Treat:
Angina Pectoris, Variant;
Angina, Stable;
Hypertension
More Information:
Definitions related to nifedipine:
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A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Calcium channel blocker used as a coronary vasodilator in the treatment of coronary insufficiency and angina.CRISP ThesaurusNational Institutes of Health, 2006
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