Biologically Active Substance
annexin
Subclass of:
Calcium-Binding Proteins
Definitions related to annexins:
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Family of proteins which bind phospholipids in the presence of calcium, believed to mediate intracellular calcium's role in membrane fusion and related events such as exocytosis; lipocortin and endonexin may also function extracellularly as inhibitors of phospholipase and blood coagulation.CRISP ThesaurusNational Institutes of Health, 2006
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Family of calcium- and phospholipid-binding proteins which are structurally related and exhibit immunological cross-reactivity. Each member contains four homologous 70-kDa repeats. The annexins are differentially distributed in vertebrate tissues (and lower eukaryotes) and appear to be involved in MEMBRANE FUSION and SIGNAL TRANSDUCTION.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(annexin family protein) A family of proteins that are capable of binding negatively charged phospholipids in a calcium-dependent manner and contain four annexin repeats. This family has been linked with a wide variety of biological processes, including inhibition of phospholipase activity, exocytosis, endocytosis, coagulation, fibrinolysis, the regulation of inflammation and membrane organization.NCI ThesaurusU.S. National Cancer Institute, 2021
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