Pharmacologic Substance
antimetabolite Audio
an·ti·me·tab·o·lite [ an-tee-muh-tab-uh-lahyt, an-tahy- ]
Subclass of:
Molecular Mechanisms of Pharmacological Action
Definitions related to antimetabolites:
  • A drug that is very similar to natural chemicals in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An antineoplastic agent with a structural similarity to a natural substance that can replace that substance in a normal biochemical pathway and interfere with the normal metabolic processes of cells.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Drug that is chemically similar to a naturally occurring metabolite, but differs enough to interfere with normal metabolic pathways.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.