A condition in which the bone marrow is unable to produce blood cells.

A syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia.

Anemia associated with a fatty, hypocellular bone marrow and global dyshematopoiesis; can be idiopathic or due to microbial, metabolic, autoimmune, or other abnormality.

Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors.

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia. The causes of aplastic anemia can include: Autoimmune disorders, which are the most common cause; Certain inherited gene changes, such as the one that can cause Fanconi anemia; Toxic substances, such as pesticides, arsenic, and benzene; Radiation therapy and chemotherapy for cancer; Certain medicines; Viral infections such as hepatitis, Epstein-Barr virus, or HIV; Pregnancy. In many people, the cause is unknown. This is called idiopathic aplastic anemia. Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include: Fatigue; Weakness; Dizziness; Shortness of breath; Easy bruising or bleeding. Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious blood disorder. If not treated, aplastic anemia can also lead to heart problems such as an arrhythmia (a problem with the rate or rhythm of your heartbeat), an enlarged heart, or heart failure. To find out if you have aplastic anemia, your doctor will: Take your medical and your family medical histories; Do a physical exam; Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood. If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include: Blood transfusions; Blood and marrow stem cell transplants; Medicines to suppress your immune system. Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly. NIH: National Heart, Lung, and Blood Institute

Aplastic anemia is defined as pancytopenia with a hypocellular marrow.

(anemia, aplastic) A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Aplastic anemia is a disorder of the hematopoietic stem cell that results in a loss of blood cell precursors, hypoplasia or aplasia of bone marrow, and cytopenias in two or more cell lines (red blood cells, white blood cells, and/or platelets). Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia...

Aplastic anemia is a syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia. Although often normocytic, mild macrocytosis can also be observed in association with stress erythropoiesis and elevated fetal hemoglobin levels.

Aplastic anemia is a condition that occurs when your body stops producing enough new blood cells. The condition leaves you fatigued and more prone to infections and uncontrolled bleeding.

Aplastic anemia is a blood disorder caused by failure of the bone marrow to make enough new blood cells. Bone marrow is a sponge-like tissue inside the bones that makes stem cells that develop into red blood cells, white blood cells, and platelets. Symptoms may include fatigue, weakness, dizziness, shortness of breath, frequent...

Aplastic anemia (AA) is defined by pancytopenia with hypocellular marrow and no abnormal cells. At least 2 of the following peripheral cytopenias must be present: Hb <10 g/dL, platelets <50 � 10^9/L, absolute neutrophil count <1.5 � 10^9/L. Bone marrow should show hypocellularity without evidence of significant dysplasia, blasts,...

Aplastic anemia, disease in which the bone marrow fails to produce an adequate number of blood cells. There may be a lack of all cell types--white blood cells (leukocytes), red blood cells (erythrocytes), and platelets--resulting in a form of the disease called pancytopenia, or there may be a lack of...