Disease or Syndrome
arthus reaction
arthus re·ac·tion
Subclass of:
Immune Complex Diseases
Definitions related to arthus reaction:
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A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A localized vasculitis resulting from deposition of antibody-antigen complexes.NCI ThesaurusU.S. National Cancer Institute, 2021
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(arthus phenomenon) Development of an inflammatory lesion a few hours after intradermal injection of antigen into a sensitized animal; the lesion results from precipitation of immune complex, which causes complement activation and tissue destruction.CRISP ThesaurusNational Institutes of Health, 2006
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Arthus phenomenon, local swelling, redness, and tissue death following skin injection of soluble antigen into a subject previously immunized by a series of similar injections. The tissue damage is a result of the precipitation of antigen-antibody complexes in the walls of the blood vessels; the...Encyclopedia Britannica, Inc., 2020
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