Disease or Syndrome
arthus reaction
arthus re·ac·tion
Subclass of:
Immune Complex Diseases
Definitions related to arthus reaction:
  • A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A localized vasculitis resulting from deposition of antibody-antigen complexes.
    NCI
    U.S. National Cancer Institute, 2021
  • (arthus phenomenon) Development of an inflammatory lesion a few hours after intradermal injection of antigen into a sensitized animal; the lesion results from precipitation of immune complex, which causes complement activation and tissue destruction.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Arthus phenomenon, local swelling, redness, and tissue death following skin injection of soluble antigen into a subject previously immunized by a series of similar injections. The tissue damage is a result of the precipitation of antigen-antibody complexes in the walls of the blood vessels; the...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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