Antibiotic
bacitracin Audio
bac·i·tra·cin [ bas-i-trey-sin ]
Brand Names:
Baciguent; Baci-IM; Bacitraycin Plus; Bacitraycin Plus Max Strength; Cortisporin Ointment; Cuadriderma; Lanabiotic; Mycitracin Plus Pain Reliever; Neo-Polycin; Neo-Polycin HC; Polycin; Polysporin; ProCoMycin; Rash Relief Antibacterial; Spectrocin Plus; Tri Biozene; Triplicin; Vetropolycin; Vetropolycin HC
Effect:
Decreased Cell Wall Synthesis & Repair
May Prevent:
Skin Diseases, Bacterial
May Treat:
Empyema; Enterocolitis, Pseudomembranous; Eye Infections, Bacterial; Pneumonia; Skin Diseases, Bacterial; Staphylococcal Infections; Streptococcal Infections
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to bacitracin:
  • A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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