• (bartter syndrome) A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• (bartter syndrome) A rare inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Patients have high levels of plasma renin concentration which is not associated with hypertension.
  NCI
  U.S. National Cancer Institute, 2021
• (bartter syndrome) A rare, inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Affected individuals have high concentration of plasma renin that is not associated with hypertension.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• (bartter's syndrome) Transmitted as an autosomal recessive trait; characterized by hypertrophy and hyperplasia of the juxtaglomerular cells, and increased concentrations of renin, angiotensin II, and aldosterone in the absence of edema and hypertension.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Bartter syndrome, originally described by Bartter and colleagues in 1962, represents a set of closely related, autosomal recessive renal tubular disorders characterized by hypokalemia, hypochloremia, metabolic alkalosis, and hyperreninemia with normal blood pressure. The underlying renal abnormality results in excessive urinary losses of...
  Medscape
  WebMD, 2025
• Bartter syndrome is a group of similar kidney disorders that cause an imbalance of potassium, sodium, chloride, and other molecules in the body. In some cases, the condition manifests before birth with increased amniotic fluid surrounding the affected fetus (polyhydramnios). Affected infants typically do not grow and gain weight as...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• Bartter syndrome, any of several rare disorders affecting the kidneys and characterized primarily by the excessive excretion of potassium in the urine. Bartter syndrome is named after American endocrinologist Frederic Bartter, who described the primary characteristics of the disorder in the early...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025