Disease or Syndrome
renal tubule acidosis
re·nal tu·bule ac·i·do·sis
Subclass of:
Renal Tubular Transport, Inborn Errors;
Acidosis
Also called:
RTA
Definitions related to renal tubular acidosis:
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(renal tubule acidosis) Rare sometimes familial disorder of the renal tubule characterized by the inability to excrete urine of normal acidity; this leads to a hyperchloremic acidosis which is often associated with one or more secondary complications such as hypercalcinuria with nephrolithiasis and nephrocalcinosis, rickets, or osteomalacia and severe potassium depletion.CRISP ThesaurusNational Institutes of Health, 2006
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A rare disorder in which structures in the kidney that filter the blood are impaired, producing urine that is more acid than normal.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Acidosis owing to malfunction of the kidney tubules with accumulation of metabolic acids and hyperchloremia, potentially leading to complications including hypokalemia, hypercalcinuria, nephrolithiasis and nephrocalcinosis.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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The inability of the kidneys to maintain acid-base homeostasis.NCI ThesaurusU.S. National Cancer Institute, 2021
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(acidosis, renal tubular) A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Renal tubular acidosis (RTA) is acidosis and electrolyte disturbances due to impaired renal hydrogen ion excretion (type 1), impaired bicarbonate resorption (type 2), or abnormal aldosterone production or response (type 4). (Type 3 is extremely rare and is not discussed.) Patients may be asymptomatic, display symptoms and signs of...Merck & Co., Inc., 2020
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The term renal tubular acidosis (RTA) describes any one of a number of disorders, in which the excretion of fixed acid (distal RTA) or the reabsorption of filtered bicarbonate (proximal RTA) is impaired to a degree that is disproportionate to any existing impairment of the glomerular filtration rate. The acid retention or bicarbonate...Athenahealth, Inc., 2019
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