• A rare syndrome characterized by vascular calcification and skin necrosis. It seen in patients with end stage renal disease.
  NCI
  U.S. National Cancer Institute, 2021
• A syndrome of vascular calcification and thrombosis with cutaneous necrosis that is usually associated with severe chronic kidney disease.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible from the Additional Information menu located on the right side of this page.
  OrphaNet
  INSERM, 2021
• Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• Calciphylaxis is a poorly understood and highly morbid syndrome of vascular calcification and skin necrosis. Bryant and White first reported it in association with uremia in 1898.
  Medscape
  WebMD, 2025
• Calciphylaxis (kal-sih-fuh-LAK-sis) is a serious, uncommon disease in which calcium accumulates in small blood vessels of the fat and skin tissues.
  Mayo Clinic
  Mayo Foundation for Medical Education and Research, 2025
• Calciphylaxis is a disease in which blood vessels (veins and arteries) become blocked by a build-up of calcium in the walls of the vessels, preventing blood from flowing to the skin or internal organs. The lack of blood flow (ischemia) damages healthy tissue and causes it to die (necrosis). The most obvious and frequent symptom of...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences