Pharmacologic Substance
canrenone
Definitions related to canrenone:
  • A synthetic pregnadiene compound with anti-aldosterone activity.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An aldosterone antagonist with potassium-sparing diuretic activity. Canrenone specifically antagonizes aldosterone at the mineralocorticoid receptor in the kidneys, thereby increasing sodium excretion and inhibiting potassium excretion. Canrenone is the primary active metabolite of both spironolactone and canreonate potassium.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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