Cell Function
clonal anergy
clon·al an·er·gy
Subclass of:
Immune Tolerance
Definitions related to clonal anergy:
  • (anergy) Diminished cellular immune responsiveness to one or more antigens.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • (anergy) Diminished immune responsiveness to specific antigens; induced or programmed clonal lymphocyte anergy is believed to be the second major mechanism (after clonal deletion) of the development of self tolerance by the immune system.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.