Organ or Tissue Function
clonal deletion
clon·al de·le·tion
Subclass of:
Immune Tolerance
Definitions related to clonal deletion:
  • Processes that result in the removal of B and T lymphocytes which have specificity for self antigens.
    NCI
    U.S. National Cancer Institute, 2021
  • Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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