Biologically Active Substance
colony-stimulating factor Audio
col·o·ny·stim·u·lat·ing fac·tor [ kah-luh-nee-stim-yoo-lay-ting fak-ter ]
Subclass of:
Hematopoietic Cell Growth Factors; Glycoproteins
Definitions related to colony-stimulating factors:
  • (colony stimulating factor) A substance that stimulates the production of blood cells. Colony-stimulating factors include granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), and promegapoietin.
    NCI
    U.S. National Cancer Institute, 2021
  • (colony stimulating factor) Glycoprotein derived from monocytes, macrophages, or stimulated lymphocytes that are required for differentiation of stem cells into granulocyte and monocyte cell colonies.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Substances that stimulate the production of blood cells. Colony-stimulating factors include granulocyte colony-stimulating factors (also called G-CSF and filgrastim), granulocyte-macrophage colony-stimulating factors (also called GM-CSF and sargramostim), and promegapoietin.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Glycoproteins found in a subfraction of normal mammalian plasma and urine. They stimulate the proliferation of bone marrow cells in agar cultures and the formation of colonies of granulocytes and/or macrophages. The factors include INTERLEUKIN-3; (IL-3); GRANULOCYTE COLONY-STIMULATING FACTOR; (G-CSF); MACROPHAGE COLONY-STIMULATING FACTOR; (M-CSF); and GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; (GM-CSF).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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