• A characteristic appearance resulting from defective ossification of craniofacial bones.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2021
• A syndrome inherited in an autosomal dominant pattern. It is characterized by early fusion of the bones of the skull and face. Patients have a distinctive facial appearance which includes low-set ears, brachycephaly, hypertelorism, exophthalmos, and mandibular prognathism.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Autosomal dominant CRANIOSYNOSTOSIS with shallow ORBITS; EXOPHTHALMOS; and maxillary hypoplasia.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Autosomal dominant disorder characterized by acrocephaly, exophthalmos, hypertelorism, strabismus, parrot-beaked nose, and hypoplastic maxilla with relative mandibular prognathism.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Crouzon syndrome was described in 1912 as one of the varieties of craniofacial dysostosis caused by premature obliteration and ossification of two or more sutures, most often coronal and sagittal. Virchow introduced the term craniostenosis.
  Medscape
  WebMD, 2019
• Crouzon syndrome is a disorder characterized by early fusion of certain skull bones (craniosynostosis). This prevents normal growth of the skull, which can affect the shape of the head and face. Signs and symptoms of Crouzon syndrome may include wide-set, bulging eyes; strabismus (misalignment of the eyes); a small, "beak-shaped" nose;...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences