Antibiotic
cyclacillin
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Haemophilus Infections; Pneumococcal Infections; Respiratory Tract Infections; Staphylococcal Infections; Urinary Tract Infections
Definitions related to cyclacillin:
  • A cyclohexylamido analog of PENICILLANIC ACID.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins, thereby inhibiting transpeptidation during peptidoglycan synthesis. This leads to an interruption of the bacterial cell wall, causing instability of bacterial cell wall and results in cell lysis. Cyclacillin is beta-lactamase susceptible.
    NCI
    U.S. National Cancer Institute, 2021
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