Antibiotic
ticarcillin
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Pseudomonas Infections; Respiratory Tract Infections; Sepsis; Skin Diseases, Infectious; Soft Tissue Infections; Urinary Tract Infections
Definitions related to ticarcillin:
  • A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.
    NCI
    U.S. National Cancer Institute, 2021
  • An antibiotic derived from penicillin similar to CARBENICILLIN in action.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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