Hormone
dehydroepiandrosterone Audio
de·hy·dro·ep·i·an·dro·ste·rone [ dee-hy-droh-eh-pee-an-dros-teh-rone ]
Brand Names:
Intrarosa
Effect:
Adrenal Medullary Activity Alteration; Enhance Penile Erection; Increased Ovarian Estrogen Secretion; Increased Testosterone Secretion
May Treat:
Adrenal Insufficiency; Dyspareunia; Lupus Vulgaris; Sexual and Gender Disorders
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to prasterone:
  • A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • (dehydroepiandrosterone) A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (dehydroepiandrosterone) A substance being studied in the prevention of cancer. It is a type of steroid.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (dehydroepiandrosterone) Major C19 steroid produced by the adrenal cortex; also produced in small quantities in the testis and the ovary; dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone; most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
    CRISP Thesaurus
    National Institutes of Health, 2006
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