Hormone
estrone Audio
es·trone [ es-trohn ]
Effect:
Bone Formation Stimulation; Decreased Follicle Stimulating Hormone Secretion; Decreased Luteinizing Hormone Secretion; Vaginal Function Alteration
May Prevent:
Osteoporosis, Postmenopausal
May Treat:
Breast Neoplasms; Hot Flashes; Hypogonadism; Menopause, Premature; Menorrhagia; Primary Ovarian Insufficiency; Prostatic Neoplasms
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to estrone:
  • An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen; converted from androstenedione directly, or from testosterone via estradiol; in humans, it is produced primarily by the cyclic ovaries, placenta, and the adipose tissue of men and postmenopausal women.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • One of three naturally occurring estrogens synthesized from androstenedione in the adrenal glands and peripheral tissues by aromatization and is the primary estrogen produced after menopause.
    NCI
    U.S. National Cancer Institute, 2021
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