Pharmacologic Substance
dicumarol
[ dahy-koo-muh-rawl, -rol, -kyoo- ]
Effect:
Decreased Coagulation Factor Activity; Decreased Coagulation Factor Concentration
May Prevent:
Pulmonary Embolism; Thromboembolism; Venous Thrombosis
May Treat:
Pulmonary Embolism; Thromboembolism; Venous Thrombosis
Definitions related to dicumarol:
  • A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
    NCI
    U.S. National Cancer Institute, 2021
  • An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.