Biologically Active Substance
elongin
Subclass of:
TRANSCRIPTION FACTOR; DNA-Binding Proteins
Definitions related to elongin:
  • A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A protein complex that is involved in the elongation of RNA transcripts.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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