Disease or Syndrome
endometriosis
en·do·me·tri·o·sis [ en-doh-mee-tree-oh-sis ]
Subclass of:
Female Genital Diseases
Etymology:
Greek endon = within + metra = uterus + -osis = condition or increase
Also called:
Endo
Definitions related to endometriosis:
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A benign condition in which tissue that looks like endometrial tissue grows in abnormal places in the abdomen.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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Condition in which tissue more or less perfectly resembling the uterine mucous membrane (the endometrium) and containing typical endometrial granular and stromal elements occurs aberrantly in various locations in the pelvic cavity.CRISP ThesaurusNational Institutes of Health, 2006
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The growth of endometrial tissue outside the uterus.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2025
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The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.NCIU.S. National Cancer Institute, 2021
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The uterus, or womb, is the place where a baby grows when a person is pregnant. The uterus is lined with tissue (endometrium). Endometriosis is a disease in which tissue that is similar to the lining of the uterus grows in other places in your body. These patches of tissue are called "implants," "nodules," or "lesions." They are most often found: On or under the ovaries; On the fallopian tubes, which carry egg cells from the ovaries to the uterus; Behind the uterus; On the tissues that hold the uterus in place; On the bowels or bladder. In rare cases, the tissue may grow on your lungs or in other parts of your body. The cause of endometriosis is unknown. Endometriosis can affect anyone who menstruates. Certain factors can raise or lower your risk of getting it. You are at higher risk if: You have a mother, sister, or daughter with endometriosis; Your period started before age 11; Your monthly cycles are short (less than 27 days); Your menstrual cycles are heavy and last more than 7 days. You have a lower risk if: You have been pregnant before; Your periods started late in adolescence; You breastfeed your babies. The main symptoms of endometriosis are: Pelvic pain, which often happens during your period.; Infertility. Other possible symptoms include: Painful menstrual cramps, which may get worse over time; Pain during or after sex; Pain in the intestine or lower abdomen; Pain with bowel movements or urination, usually during your period; Heavy periods; Spotting or bleeding between periods; Digestive or gastrointestinal symptoms; Fatigue or lack of energy. Surgery is the only way to know for sure that you have endometriosis. First, however, your health care provider will ask about your symptoms and medical history. You will have a pelvic exam and may have some imaging tests. The most common surgery to diagnose endometriosis is a laparoscopy. This is a type of surgery that uses a laparoscope, a thin tube with a camera and light. The surgeon inserts the laparoscope through a small cut in the skin near your belly button. Your provider can make a diagnosis based on how the patches of endometriosis look. They may also do a biopsy to get a tissue sample. There is no cure for endometriosis, but there are treatments for the symptoms. Your provider will work with you to decide which treatments would be best for you. Treatments for endometriosis pain include: Pain relievers, including nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen and a prescription medicine specifically for endometriosis. Providers may sometimes prescribe opioids for severe pain.; Hormone therapy, which stops the ovaries from making hormones. This may slow the growth of the endometrial tissue and may prevent new areas from growing. Types of hormone therapy include: Birth control pills.; Progestin therapy.; Gonadotropin-releasing hormone (GnRH) medicines (GnRH agonists and antagonists). These medicines cause a temporary menopause. After your stop taking the medicines, your menstrual periods will start again, and pregnancy is possible.; Surgical treatments for severe pain, including procedures to remove the endometriosis patches or cut some nerves in the pelvis. The surgery may be a laparoscopy or major surgery. Treatments for infertility caused by endometriosis include: Laparoscopy to remove the endometriosis patches; In vitro fertilization. NIH: National Institute of Child Health and Human DevelopmentMedlinePlusU.S. National Library of Medicine, 2025
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In endometriosis, functioning endometrial tissue is implanted in the pelvis outside the uterine cavity. Symptoms depend on location of the implants and may include dysmenorrhea, dyspareunia, infertility, dysuria, and pain during defecation. Severity of symptoms is not related to disease stage. Diagnosis is by direct visualization and...Merck & Co., Inc., 2025
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Ectopic endometrial tissues are most commonly located in the dependent portions of the female pelvis (eg, posterior and anterior cul-de-sac, uterosacral ligaments, tubes, ovaries), but any organ system is potentially at risk (see the following images).These ectopic foci respond to cyclic hormonal fluctuations in much the...WebMD, 2025
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Endometriosis (en-doe-me-tree-O-sis) is an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus - the endometrium - grows outside your uterus. Endometriosis most commonly involves your ovaries, fallopian tubes and the tissue lining your pelvis. Rarely, endometrial tissue may spread...Mayo Foundation for Medical Education and Research, 2025
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Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity and uterine musculature. Surgical appearance varies significantly from superficial blebs to infiltrating fibrosis. Direct visualization confirmed by histological examination remains essential for diagnosis.Athenahealth, Inc., 2019
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Endometriosis, disorder of the female reproductive system characterized by the growth of endometrial tissue (uterine lining) in an abnormal location. Rather than flowing out of the uterus by way of the vagina (during menstruation), some fragments of the endometrium may leave via the fallopian tubes...Encyclopedia Britannica, Inc., 2025
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