Neoplastic Process
ependymoma
[ eh-pen-dih-moh-muh ]
Subclass of:
Glioma
Etymology:
Greek ependyma = an outer garment or wrap + -oma = neoplasm or tumor
Definitions related to ependymoma:
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A malignant neoplasm arising from ependymal cells that line the ventricles of the brain and the central canal of the spinal cord.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A type of brain tumor that begins in cells lining the spinal cord central canal (fluid-filled space down the center) or the ventricles (fluid-filled spaces of the brain). Ependymomas may also form in the choroid plexus (tissue in the ventricles that makes cerebrospinal fluid).NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)NCI ThesaurusU.S. National Cancer Institute, 2021
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Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Gliomas derived from ependymocytes that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults; may arise from any level of the ventricular system or central canal of the spinal cord; intracranial ependymomas most frequently originate in the fourth ventricle and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes; spinal ependymomas are usually benign papillary or myxopapillary tumors.CRISP ThesaurusNational Institutes of Health, 2006
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The presence of an ependymoma of the central nervous system.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Ependymomas are slow-growing central nervous system tumors that involve the ventricular system. Diagnosis is based on MRI and biopsy. Treatment is a combination of surgery, radiation therapy, and chemotherapy.Merck & Co., Inc., 2020
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Ependymomas are glial tumors that arise from ependymal cells within the central nervous system (CNS). They were first described by Bailey in 1924.WebMD, 2019
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Ependymoma is a type of tumor that can form in the brain or spinal cord. Ependymoma begins in the ependymal cells in the brain and spinal cord that line the passageways where the fluid (cerebrospinal fluid) that nourishes your brain flows.Mayo Foundation for Medical Education and Research
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Ependymoma is the most frequent intramedullary tumor in adults (but accounts for only 10-12% of pediatric central nervous system tumors), and can be benign or anaplastic. Ependymoma arise from the ependymal cells of the cerebral ventricles, corticle rests and central canal of the spinal cord, and manifest with variable symptoms such...National Center for Advancing Translational Sciences
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