Pharmacologic Substance
epoetin alfa Audio
[ ih-poi-i-tn al-fuh ]
Brand Names:
Epogen; Procrit; Retacrit
Effect:
Increased Erythroid Cell Production
May Treat:
Anemia
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to epoetin alfa:
  • A recombinant glycosylated form of erythropoietin which stimulates the differentiation and proliferation of erythroid precursors. It is used for the treatment of ANEMIA associated with CHRONIC RENAL FAILURE in dialysis and predialysis patients.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily by cells of the peritubular capillary endothelium of the kidney in response to hypoxia, circulating EPO binds to EPO receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their replication and maturation into functional erythrocytes.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A substance that is made in the laboratory and stimulates the bone marrow to make red blood cells. It is a type of antianemic and a type of recombinant human erythropoietin.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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