Pharmacologic Substance
famotidine
Brand Names:
Duexis; Duo Fusion; Pepcid; Pepcid Complete; Tums Dual Action
Effect:
Decreased Histamine Activity; Inhibition Gastric Acid Secretion
May Prevent:
Duodenal Ulcer; Gastrointestinal Hemorrhage; Stomach Ulcer
May Treat:
Duodenal Ulcer; Dyspepsia; Esophagitis, Peptic; Gastroesophageal Reflux; Heartburn; Helicobacter Infections; Stomach Ulcer; Urticaria; Zollinger-Ellison Syndrome
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to famotidine:
  • A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
    NCI
    U.S. National Cancer Institute, 2021
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