Pharmacologic Substance
fenfluramine Audio
fen·flu·ra·mine [ fen-floo r-uh-meen ]
Brand Names:
Fintepla
Effect:
Appetite Suppression; Increased Serotonin Activity
May Treat:
Autistic Disorder; Bulimia; Obesity
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to fenfluramine:
  • A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Centrally active phenethylamine that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.