Pharmacologic Substance
pseudoephedrine Audio
pseu·do·e·phed·rine [ soo-doh-i-fed-rin, -ef-i-dreen, -drin ]
Brand Names:
Alavert D; Allegra-D; Allerclear; Aller-Tec D; Ambifed CD; Ambifed-G CD; Aphedrid; A-Phedrin; Biotussin; Bromfed DM; Bromplex HD; Cetiri-D; Cheratussin DAC; Clarinex-D; Claritin-D; Codar D; Contac Cold; Drixoral Non-Drowsy; Genac brand of pseudoephedrine/triprolidine; Genaphed; Histafed; Hycofenix; Lortuss EX; Mar-cof BP; M-End Max D; Nasofed; Nexafed; Nucofed; P-V-Tussin; Q-Fed; Semprex-D; Stahist AD; Statuss Green Reformulated Jan 2012; Sudafed; Sudogest; Su-Tuss HD; Tekral; Vi-Sudo; Wal Zyr D; Wal-Act; Wal-Dryl-D Allergy; Wal-Fex D; Wal-itin D; Wal-Phed; Zephrex-D; Zodryl DAC; Zodryl DEC; Zyrtec-D
Effect:
Bronchodilation; Vasoconstriction
May Treat:
Asthma; Common Cold; Rhinitis, Allergic, Perennial; Sinusitis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to pseudoephedrine:
  • A decongestant drug that may also relieve mild incontinence.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A phenethylamine and a diastereomer of ephedrine with sympathomimetic property. Pseudoephedrine displaces norepinephrine from storage vesicles in presynaptic neurones, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors. It also has weak direct agonist activity at alpha- and beta- adrenergic receptors. Receptor stimulation results in vasoconstriction and decreases nasal and sinus congestion.
    NCI
    U.S. National Cancer Institute, 2021
  • A phenethylamine that is an isomer of EPHEDRINE which has less central nervous system effects and usage is mainly for respiratory tract decongestion.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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