Disease or Syndrome
gastroesophageal reflux
gas·tro·oe·soph·a·ge·al re·flux dis·ease [ gas-troh-i-sof-uh-jee-uhl, ee-suh-faj-ee-uhl, gas- ]
Subclass of:
Esophageal motility disorders
Also called:
GERD
Definitions related to gastroesophageal reflux disease:
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(gerd) Your esophagus is the tube that carries food from your mouth to your stomach. Gastroesophageal reflux disease (GERD) happens when a muscle at the end of your esophagus does not close properly. This allows stomach contents to leak back, or reflux, into the esophagus and irritate it. You may feel a burning in the chest or throat called heartburn. Sometimes, you can taste stomach fluid in the back of the mouth. If you have these symptoms more than twice a week, you may have GERD. You can also have GERD without having heartburn. Your symptoms could include a dry cough, asthma symptoms, or trouble swallowing. Anyone, including infants and children, can have GERD. If not treated, it can lead to more serious health problems. In some cases, you might need medicines or surgery. However, many people can improve their symptoms by Avoiding alcohol and spicy, fatty or acidic foods that trigger heartburn; Eating smaller meals; Not eating close to bedtime; Losing weight if needed; Wearing loose-fitting clothes. NIH: National Institute of Diabetes and Digestive and Kidney DiseasesMedlinePlusU.S. National Library of Medicine, 2021
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(gastroesophageal reflux) Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.NCI ThesaurusU.S. National Cancer Institute, 2021
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Reflux of stomach contents with symptoms and/or complications from the reflux act.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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Incompetence of the lower esophageal sphincter allows reflux of gastric contents into the esophagus, causing burning pain. Prolonged reflux may lead to esophagitis, stricture, and rarely metaplasia or cancer. Diagnosis is clinical, sometimes with endoscopy, with or without acid testing. Treatment involves lifestyle modification, acid...Merck & Co., Inc., 2020
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Schematically, the esophagus, lower esophageal sphincter (LES), and stomach can be envisioned as a simple plumbing circuit as described by Stein and coworkers. The esophagus functions as an antegrade pump, the LES as a valve, and the stomach as a reservoir.WebMD, 2019
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Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). This backwash (acid reflux) can irritate the lining of your esophagus.Mayo Foundation for Medical Education and Research
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The American College of Gastroenterology defines GERD as "symptoms or complications resulting from the reflux of gastric contents into the esophagus or beyond, into the oral cavity (including larynx) or lung." Typical symptoms are heartburn and acid regurgitation. Atypical symptoms include cough, laryngitis, asthma, or dental erosion....Athenahealth, Inc., 2019
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