Molecular Biology Research Technique
gene targeting
[ jeen tahr-git-ing ]
Subclass of:
Genetic Techniques
Definitions related to gene targeting:
  • A technique that involves integration of an exogenous DNA sequence encoding a specific gene into the genome of an organism by homologous recombination.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Genetic technique creating a recombinational event that produces exchange between DNA introduced into a cell and its homologous chromosomal target; involves two steps: pairing of DNA strands at the region of homology, and DNA strand exchange.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.