• A rare pancreatic tumor that produces a hormone called glucagon. Glucagonomas can produce symptoms similar to diabetes.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• An almost always malignant GLUCAGON-secreting tumor derived from the PANCREATIC ALPHA CELLS. It is characterized by a distinctive migratory ERYTHEMA; WEIGHT LOSS; STOMATITIS; GLOSSITIS; DIABETES MELLITUS; hypoaminoacidemia; and normochromic normocytic ANEMIA.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• An endocrine tumor of the pancreas that secretes excessive amounts of glucagon.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2021
• (pancreatic glucagonoma) A usually malignant, glucagon-producing neuroendocrine tumor arising from the pancreatic alpha cells. It may be associated with necrolytic erythema migrans, diarrhea, diabetes, glossitis, weight loss, malabsorption, and anemia. Almost 25% of patients experience thromboembolic complications, and 50% have liver metastases at the time of diagnosis.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• A glucagonoma is a pancreatic alpha-cell tumor that secretes glucagon, causing hyperglycemia and a characteristic rash. Diagnosis is by elevated glucagon levels and imaging studies. Tumor is localized with CT and endoscopic ultrasonography. Treatment is surgical resection.
  Merck Manuals
  Merck & Co., Inc., 2020
• A glucagonoma is a rare neuroendocrine tumor with nearly exclusive pancreatic localization. Malignant glucagonomas are islet cell pancreatic tumors that are discovered because of glucagonoma syndrome (in which the glucagonoma autonomously secretes glucagon), because of local mass effects, or incidentally.
  Medscape
  WebMD, 2019
• Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences