Pharmacologic Substance
guanfacine
Brand Names:
Intuniv
Effect:
Decreased Blood Pressure; Systemic Arterial Vasodilation; Systemic Venous Vasodilation
May Treat:
Attention Deficit Disorder with Hyperactivity; Hypertension
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to guanfacine:
  • A centrally acting adrenergic agonist with non-stimulant and antihypertensive property. Guanfacine selectively stimulates alpha-2 adrenergic receptors in the central nervous system, thereby resulting in inhibition of sympathetic nervous system outflow. Used alone or in combination with other drugs, this agent causes reduction of peripheral and renal vascular resistance, and lowers both systolic and diastolic blood pressure and heart rate.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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