Pharmacologic Substance
halcinonide
Brand Names:
Halog
Effect:
Antipruritic Activity; Decreased Immunologically Active Molecule Activity; Decreased Protein Synthesis; Vasoconstriction
May Treat:
Facial Dermatoses; Foot Dermatoses; Hand Dermatoses; Inflammation; Leg Dermatoses; Scalp Dermatoses
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to halcinonide:
  • A glucocorticoid used topically in the treatment of DERMATITIS; ECZEMA; or PSORIASIS. It may cause skin irritation.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05)
    NCI
    U.S. National Cancer Institute, 2021
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