Disease or Syndrome
histoplasmosis
his·to·plas·mo·sis [ his-toh-plaz-moh-sis ]
Subclass of:
Mycoses
Etymology:
Greek histos = web or tissue + plasma = a thing formed + -osis = condition
Hence infection with Histoplasma.
Hence infection with Histoplasma.
Definitions related to histoplasmosis:
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A disease caused by the fungus Histoplasma capsulatum. It primarily affects the lungs but can also occur as a disseminated disease that affects additional organs. The acute respiratory disease has symptoms similar to those of a cold or flu and it usually resolves without treatment in healthy individuals. The disseminated form is generally fatal if untreated.NCIU.S. National Cancer Institute, 2021
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An often self-limited infection that is caused by Histoplasma capsulatum, which typically manifests as a flu-like illness, but severe disseminated disease can occur.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Histoplasmosis is an infection caused by a fungus called Histoplasma. This fungus is common in the central and eastern United States, especially around the Ohio and Mississippi River valleys. It can also be found in parts of Central and South America, Africa, Asia, and Australia. It lives in the environment, especially in soil that contains large amounts of bat or bird droppings (poop). You get histoplasmosis by breathing in Histoplasma fungal spores from the air. It usually happens after you have been doing an activity that disturbs the soil, such as farming, construction, and landscaping. Histoplasmosis is not contagious. This means that you cannot get the infection from another person or an animal. Most people who breathe in the spores never have any symptoms. If you do get symptoms, they usually start between 3 and 17 days after you breathe in the spores. The symptoms may include: Fever; Cough; Fatigue; Chills; Headache; Chest pain; Body aches. For most people, the symptoms of histoplasmosis will go away within a few weeks to a month. However, some people can have symptoms that last longer, especially if their infection becomes severe. Certain people are more likely to get a severe infection: People who have weakened immune systems, for example from: Having HIV; Having had an organ transplant; Taking medicines which weaken your immune system, such as chemotherapy and steroids.; Infants; Adults age 55 and over. Severe histoplasmosis can develop into a long-term lung infection. It can also spread from the lungs to other parts of the body, such as the central nervous system (the brain and spinal cord). This is known as disseminated histoplasmosis. To find out if you have histoplasmosis, your health care provider: Will ask about your symptoms and your medical and travel history; Will do a physical exam; Will likely order a blood, urine, or tissue test to look for signs of the fungus; May order a chest x-ray or CT scan of the lungs. For some people, the symptoms of histoplasmosis will go away without treatment. But you will need treatment if you have severe histoplasmosis in the lungs, chronic histoplasmosis, or an infection that has spread to other parts of the body. That treatment would be with prescription antifungal medicines. In some cases, you may need to take the medicines for 3 months to 1 year. Centers for Disease Control and PreventionMedlinePlusU.S. National Library of Medicine, 2025
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Histoplasmosis is caused by the fungus Histoplasma capsulatum and is consider to be an opportunistic infection in immunosuppressed persons.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2025
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Infection resulting from exposure to the fungus HISTOPLASMA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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Infection resulting from inhalation or ingestion of spores of the fungus of the genus Histoplasma; worldwide in distribution and particularly common in the midwestern United States.CRISP ThesaurusNational Institutes of Health, 2006
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Histoplasmosis is a pulmonary and hematogenous disease caused by Histoplasma capsulatum; it is often chronic and usually follows an asymptomatic primary infection. Symptoms are those of pneumonia or of nonspecific chronic illness. Diagnosis is by identification of the organism in sputum or tissue or use of specific serum and urine...Merck & Co., Inc., 2025
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Histoplasma capsulatum is a dimorphic fungus that remains in a mycelial form at ambient temperatures and grows as yeast at body temperature in mammals. Infection causes histoplasmosis.WebMD, 2025
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Histoplasmosis is an infection caused by breathing in spores of a fungus often found in bird and bat droppings. The infection is most commonly spread when these spores are inhaled after taking to the air, such as during demolition or cleanup projects.Mayo Foundation for Medical Education and Research, 2025
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Histoplasmosis is an infectious disease caused by the fungus Histoplasma capsulatum . It is not communicable from person to person but is acquired from inhalational exposure to infectious spores found in soil contaminated with bird or bat droppings. African histoplasmosis is a different clinical entity and will not be discussed here.Athenahealth, Inc., 2019
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Histoplasmosis, infection with the fungus Histoplasma capsulatum, occurring in humans and other animals. The disease is contracted by the inhalation of dust containing spores of the fungus. H. capsulatum prefers moist, shady conditions and is found in woods, caves, cellars, silos, and old chicken...Encyclopedia Britannica, Inc., 2025
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