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Related terms:
alpha-thalassemia
edema
erythroblastosis fetalis
kernicterus
Disease or Syndrome
hydrops fetalis
Subclass of:
Erythroblastosis, Fetal; alpha-Thalassemia; Edema
Definitions related to hydrops fetalis:
  • A condition characterized by fluid accumulation in two or more anatomic compartments in the fetus.
    NCI
    U.S. National Cancer Institute, 2021
  • Abnormal accumulation of serous fluid in two or more fetal compartments, such as SKIN; PLEURA; PERICARDIUM; PLACENTA; PERITONEUM; AMNIOTIC FLUID. General fetal EDEMA may be of non-immunologic origin, or of immunologic origin as in the case of ERYTHROBLASTOSIS FETALIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Hydrops fetalis is a severe and challenging fetal condition usually defined as the excessive accumulation of fetal fluid within the fetal extravascular compartments and body cavities that manifests as edema, pleural and pericardial effusion and ascites. It is the end-stage of a wide variety of disorders. The cause may be immunologic (immune hydrops fetalis, IHF) or non immunologic (non-immune hydrops fetalis, NIHF), depending on the presence or absence of maternal antibodies against fetal red cell antigens (ABO incompatibility or rhesus (Rh) incompatibility).
    OrphaNet
    INSERM, 2021
  • The abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Hydrops fetalis is Latin for edema of the fetus. Ballantyne first described hydrops fetalis in 1892, although this condition had been recognized for almost 200 years.
    Medscape
    WebMD, 2025
  • Hydrops fetalis is a serious condition in which abnormal amounts of fluid build up in two or more body areas of a fetus or newborn. There are two types of hydrops fetalis: immune and nonimmune. Immune hydrops fetalis is a complication of a severe form of Rh incompatibility. Rh compatibility causes massive red blood cell destruction,...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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