Immunologic Factor
immunoglobulin idiotype
[ im-yuh-noh-glob-yuh-lin, ih-myoo- id-ee-uh-tahyp ]
Subclass of:
Immunoglobulin Variable Region; Immunoglobulin Fragments; Immunogenetic Phenomena; Epitopes
Definitions related to immunoglobulin idiotypes:
  • (idiotype) The antigenic specificity of an antibody as determined by the unique sequence of its antigen combining site.
    NCI
    U.S. National Cancer Institute, 2021
  • Unique, genetically controlled determinants present on antibodies whose specificity is limited to a single group of proteins such as another antibody molecule or an individual myeloma protein; the idiotype appears to represent the antigenicity of the antigen binding site of the antibody and to be genetically codetermined with it; the idiotypic determinants have been precisely located to the immunoglobulin variable region of both immunoglobin polypeptide chains.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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