• A condition in which the body produces insulin but can't use it properly. This leads to diabetes.
  Harvard Dictionary of Health Terms
  Harvard Medical Publishing, 2011
• Decreased insulin signaling such that the glycemic response to a given amount of insulin is reduced.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• Decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2021
• Insulin resistance is a state in which a given concentration of insulin produces a less-than-expected biological effect. (See Pathophysiology.
  Medscape
  WebMD, 2019