Pharmacologic Substance
ketotifen
Brand Names:
Alaway; Claritin Eye; Wal-Zyr Itchy Eye; Zaditor
Effect:
Decreased Histamine Activity
May Prevent:
Rhinitis, Allergic, Perennial
May Treat:
Conjunctivitis, Allergic
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to ketotifen:
  • A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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