Pharmacologic Substance
ketanserin
Definitions related to ketanserin:
  • 3-(2-(4-(p-fluorobenzoyl)-piperidino) ethyl)-2,4-quinazolinedione.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • A quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration, ketanserin binds to and inhibits the signaling mediated by 5-HTR2, which inhibits serotonin-dependent vasoconstriction and platelet activation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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