Disease or Syndrome
lactic acidosis
lac·tic ac·i·do·sis [ lak-tik as-i-doh-sis ]
Subclass of:
Acidosis
Definitions related to acidosis, lactic:
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(lactic acidosis) A rare but potentially lethal condition in which blood lactic acid levels increase.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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(lactic acidosis) An abnormal buildup of lactic acid in the body, leading to acidification of the blood and other bodily fluids.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(lactic acidosis) Metabolic acidosis characterized by the accumulation of lactate in the body. It is caused by tissue hypoxia.NCI ThesaurusU.S. National Cancer Institute, 2021
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Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Lactic acidosis is a high anion gap metabolic acidosis due to elevated blood lactate. Lactic acidosis results from overproduction of lactate, decreased metabolism of lactate, or both.Merck & Co., Inc., 2020
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In basic terms, lactic acid is the normal endpoint of the anaerobic breakdown of glucose in the tissues. The lactate exits the cells and is transported to the liver, where it is oxidized back to glucose.WebMD, 2019
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