Pharmacologic Substance
mebendazole
[ muh-ben-duh-zohl ]
Brand Names:
Emverm; Vermox
Effect:
Decreased Glucose Transport into Cells
May Treat:
Ancylostomiasis; Ascariasis; Enterobiasis; Trichuriasis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to mebendazole:
  • A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for survival and reproduction of the helminth. This eventually causes the helminths death.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.