Indicator, Reagent, or Diagnostic Aid
bisbenzimidazole
Subclass of:
Benzimidazoles
Definitions related to bisbenzimidazole:
  • (pibenzimol) A fluorescent dye of benzimidazole derivative. Pibenzimol binds to AT-specific sites in the minor groove of duplex DNA and inhibits topoisomerase I, and DNA polymerase, thereby preventing DNA replication. This agent prolongs the G2 phase of the cell cycle and initiates apoptosis in tumor cells. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.