Pharmacologic Substance
metronidazole Audio
met·ro·ni·da·zole [ me-truh-nahy-duh-zohl ]
Brand Names:
Flagyl; MetroCream; MetroGel; MetroLotion; Noritate; Nuvessa; Nydamax; Pylera; Rosadan; Vandazole
Effect:
Decreased Protein Synthesis; DNA Integrity Alteration; Increased Cellular Death
May Prevent:
Trichomonas Infections
May Treat:
Abscess; Amebiasis; Bacteroides Infections; Endocarditis, Bacterial; Enterocolitis, Pseudomembranous; Giardiasis; Helicobacter Infections; Meningitis, Bacterial; Rosacea; Sepsis; Surgical Wound Infection; Trichomonas Vaginitis; Vaginosis, Bacterial
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to metronidazole:
  • A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.
    NCI
    U.S. National Cancer Institute, 2021
  • Antiprotozoal and antibacterial effective against obligate anaerobes.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.