Pharmacologic Substance
nimorazole
May Prevent:
Protozoan Infections
May Treat:
Head and Neck Neoplasms; Hypoxia; Trichomonas Infections
Definitions related to nimorazole:
  • A water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity. As an oxygen mimetic, nimorazole induces free radical formation and is able to sensitize hypoxic cells to the cytotoxic effects of ionizing radiation. This prevents DNA repair and thus enhances damage to DNA strands; eventually, leading to tumor cell death. Nimorazole is less active but also less toxic than the 2-nitroimidazole compounds, misonidazole and etanidazole.
    NCI
    U.S. National Cancer Institute, 2021
  • An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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