Antibiotic
novobiocin Audio
[ noh-voh-by-oh-sin ]
Brand Names:
Albadry
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to novobiocin:
  • An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An antibiotic drug used to treat infection.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Antibiotic obtained from Streptomyces, effective chiefly against Staphylococcci and other gram-positive organisms.
    CRISP Thesaurus
    National Institutes of Health, 2006
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